How to Pay Less for Entresto: Medicare, Coupons, and International Options

Patients prescribed patented, brand-name medicines that have yet to face competition from generic drugmakers are too often subjected to unimaginably high prescription drug bills. The result is a hunt for ways to save, be it through patient assistance programs, pharmacy discount coupons, or international mail order. Such is the case for those prescribed the heart failure drug Entresto. You may have seen that the Medicare negotiated price for Entresto is $295 for a 30-day supply. This is the price Medicare will pay in 2026. If you are a Medicare beneficiary, your copay will hopefully be significantly less. Plus, in 2025, your out-of-pocket cost through Medicare will be capped at $2000/year. Until then, PharmacyChecker has compared some savings options for Americans and patients who live elsewhere and may benefit from international mail order for access to affordable medicines. If you are having trouble affording your Entresto prescription, the information below may help you adhere to your prescribed drug therapy. 

Related: Medicare Negotiated Drug Prices 4.7 Times Higher Than NHS Negotiated Prices

Entresto is on some Medicare and private U.S. insurance coverage plan formularies. If you find the copay still prohibitively high, discuss how the cash price might be lower with your pharmacist. Compare discount coupon prices, which can be applied to that cash price, offered by pharmacies in your zip code. Novartis, the drug company that markets Entresto in the U.S. (and elsewhere), offers financial support options on Entresto.com – they advertise that commercially insured patients may be eligible to “pay as little as $10 for up to a 90-day supply.” 

Entresto International Price Comparison

Based on PharmacyChecker price comparisons, Entresto is as low as $1.21 per 24/26mg tablet via an international online pharmacy. If you are in the U.S., we compare coupon prices among independent and chain pharmacies, such as Walgreens and CVS. The lowest coupon price is around $11 per tablet. At an 89% savings, the online pharmacy price is definitely more affordable. PharmacyChecker only lists prices of online pharmacies that are accredited through its International Pharmacy Verification Program (IPVP). This means that all international online pharmacy prices compared on PharmacyChecker.com are offered by reputable, trustworthy sources that PharmacyChecker inspects and monitors against its high standards of pharmacy safety. 

PharmacyChecker drug price comparisons 2024. Prices are for a quantity of 60 tablets. What does IPVP Accredited mean?

PharmacyChecker frequently highlights the global nature of our pharmaceutical supply chain. Entresto sold in the U.S. is manufactured by Novartis in Singapore. Entresto Sprinkle sold in the U.S. is manufactured by Novartis in Slovenia. In general, the names and strengths of drugs can vary globally due to differing marketing strategies. This is the case with sacubitril/valsartan (brand names: Entresto, Vymada, CIDMUS, Oneptus, Azmarda, Neparvis, Sacurise). Any variations need to be approved by your prescriber. 

Novartis markets sacubitril/valsartan under the name Entresto in the United States, UK, and Canada with the strengths 24/26 mg, 49/51 mg, and 97/103 mg.

Novartis markets sacubitril/valsartan in India and South Africa under the name Vymada with strengths 50mg, 100mg, and 200mg.

Dr. Reddy’s markets sacubitril/valsartan in India under the name CIDMUS with the strengths 50mg, 100mg, and 200mg. Cipla also markets sacubitril/valsartan under those same strengths in India. Sun Pharma markets it under the name Sacurise with those same strengths.

Novartis markets sacubitril/valsartan in Turkey under the name Oneptus with strengths of 24/26 mg, 49/51 mg, and 97/103 mg. 

PharmacyChecker has also seen sacubitril/valsartan sold under the brand names Azmarda (in India) and Neparvis (in Europe).